One concern for any human being adopting a scientific worldview is that science consciously strives to disregard its humanity. In fact it is more extreme than this. Science regards its inhumanity as a virtue.
This focus on a reality beyond the subjective - a reality beyond the human - institutes a conflict between science, rationality and humanity. While this focus on an objective universe has entirely rational arguments - and seems like an entirely rational ambition - there remains the question of how rational it is for science to privilege this particular fiction over the welfare of individuals.
It is a determination that betrays a radical ambivalence towards human beings, as a cure for cancer and a nuclear weapon might be said to demonstrate. This perversity is compounded by the insurmountable obstacle any subjective individual faces when they try to comment on an objective world.